Long-term lithium treatment in bipolar disorder effects
Background. Concerns about potential adverse effects of long-term exposure to lithium as a mood-stabilizing treatment notably include altered renal function. However, the incidence of severe renal dysfunction; rate of decline over time; effects of lithium dose, serum concentration. Other common side effects such as nausea and headache, can be generally remedied by a higher intake of water. lithium unbalances significance of such changes is not clear but is of sufficient concern to discourage long-term use of lithium unless it is definitely indicated. The adverse effects occurred early in treatment HR 1 for length of treatment with lithium. Because lithium remains a treatment of choice for bipolar disorder, patients need baseline measures of renal, thyroid, and parathyroid function and regular long-term monitoring.
Can anyone tell me what the long term effects of lithium
May 20, 2015. Lithium is a widely used and highly effective treatment for mood disorders, but causes poorly characterised adverse effects in kidney and. I am not bi-polar but suffer from severe recurrent depression. I would like to know the effects both reversal and irreversible of long term lithium use? I have regular blood tests where thyroid and liver function are checked. Long-term effects of lithium on renal function. Authors Mohamad Zaidan France 2 Paris Descartes University France.
Lithium Treatment for Bipolar Disorder Side Effects and
Sometimes, side effects of lithium can be relieved by tweaking the dose. Also, in some people, long-term lithium treatment can interfere with kidney function or lead to permanent kidney damage -- which is why periodic monitoring of blood tests to measure kidney functioning is important. Other toxic effects of lithium include coarse tremor, muscle twitching, convulsions and renal failure.66 People who survive a poisoning episode may developThe significance of such changes is not clear, but is of sufficient concern to discourage long-term use of lithium unless it is definitely indicated.