Clopidogrel and Proton Pump Inhibitors A New Drug Interaction?
Clopidogrel is a thienopyridine platelet antagonist that irreversibly inhibits the. Other PPIs, such as pantoprazole and esomeprazole, have demonstrated less. A Major Drug Interaction exists between Nexium IV and Plavix. View detailed information regarding this drug interaction. Of patients in the omeprazole group, 60.9% had a poor response versus. the effect of pantoprazole or esomeprazole and clopidogrel on platelet activity by.
Nexium IV and Plavix Drug Interactions -
May 14, 2012. Keywords Clopidogrel, Thienopyridine, Proton pump inhibitors, Drug. Clopidogrel versus aspirin and esomeprazole to prevent recurrent. Jan 20, 2005. Original Article from The New England Journal of Medicine — Clopidogrel versus Aspirin and Esomeprazole to Prevent Recurrent Ulcer. Nov 17, 2009. The FDA warns patients on Plavix not to take Nexium or Prilosec -- or nine other drugs, including Prozac and Tagamet. The drugs keep Plavix.
Clopidogrel-PPI Interaction Questioned in Meta-analysis - Medscape
Jan 27, 2015. Among 30 observational studies, investigators report that patients treated with aspirin and clopidogrel for unstable angina/NSTEMI who. Nov 1, 2016. The U. S. Food and Drug Administration FDA is reminding the public that it continues to warn against the concomitant use of Plavix.